I had a chance to speak with a Russ Humphries who is the Sr. Product Manager for the Windows VISTA Security team and was very impressed with this man's overall intelligence, but especially impressed with a technology called BitLocker. I dont' want to go into it at the moment as I'm a bit short on time, but it's basically a mechanism for very securely encrypting content on disk in such a manner that nobody can retrieve it regardless of their manner of attack.
Check out this site here for more information (I'll try reducing it to something more palletable later): http://www.microsoft.com/technet/windowsvista/security/bitlockr.mspx.